Chemotherapy drugs

1) Docetaxel--trade name: Taxotere

Part of a group of drugs called taxanes that affect cell mitosis. Stops the growth of cancer cells causing the cells to die.

Antinausea medication is given before the Taxotere.

Lowers blood counts (white blood cells, red blood cells, and platelets).
Can lower white cell count ~~9 days after it is given causing risk of infection.

Lowers platelet counts increasing risk of bleeding.

Side effects:
-decreased WBC count
-decreased platelet count
-hair thinning or loss
-loss of appetite
-nausea
-vomiting
-nail changes
-mouth sores

2) Doxorubicin hydrochloride--trade name Adriamycin

Part of a group of drugs called anthracycline antibiotics that stop growth of cancer cells causing the cells to die.

Pretty red color which then causes urine to become red for 1-2 days.

Also lowers blood counts especially WBCs 10-14 days after drug is given. Can cause severe nausea and vomiting.

Side effects:
-lowered WBC count
-lowered platelet count
-loss of appetite
-darkening of nail beds and skin creases of hands
-hair loss
-nausea
-vomiting
-mouth sores

3) Cyclophosphamide--trade name Cytoxan

Part of a group of drugs called alkylating agents that stop the growth of cancer cells causing them to die.

Can lower blood counts especially WBC 1 to 2 weeks after drug is given.

Side effects:
-decreased WBC count
-hair loss
-nausea
-vomiting
-loss of appetite
-mouth sores
-diarrhea
-acne
-darkening of nail beds